As many as four fundamental research ideas of KIT convinced the European Research Council (ERC). The leading researchers will now be granted nearly EUR 150,000 in addition to tap the full innovative potential of their results. The so-called “Proof of Concept Grants” serve to further develop application-relevant research results for the market. The four projects focus on the analysis of biological samples, data transmission, and the microstructuring of materials.
HYPHEN – Hybrid Photonic Engines for Massive Cloud Connectivity
Digital data traffic increases constantly, which causes bottlenecks at the large data centers, where the queries of millions of users meet. New technologies for optical wavelength-division multiplexing (WDM) in glass fibers might increase data speed at and between data centers by an order of magnitude, but they are still highly complex and, hence, not efficient from an economic point of view. The HYPHEN project headed by Christian Koos is aimed at developing a novel concept based on the integration of optical components on microchips and, hence, at designing compact emitter and receiver units for WDM. The concept is expected to result in great market potentials that are to be further developed under the project. Eventually, a spinoff company is to be established.
Press release on Prof. Koos‘ ERC Grant (2011):
LiVoX – Magic Angle Coil Spinning NMR on Living Voxels
By means of NMR methods, molecules can be analyzed in detail or detected in samples. Apart from fundamental research, they may be applied for the examination of food and medical substances or for the investigation of tissue samples in e.g. cancer therapy. The LiVoX project headed by Jan Korvink will scale up the production process of chip-based NMR sensors that have been used as prototypes in laboratories so far for industrial series production. In cooperation with the spinoff Voxalytic GmbH, the production steps will be checked for scalability and quality controls will be defined.
Further information on Prof. Korvink’s research:
PreScreenArrays – Peptide Arrays as Pre-screening Tool
Peptides are important reaction partners in biological processes, but may also be modified for use in engineering. The organic molecules consist of very long chains of various amino acids, whose precise sequence determines the properties of the peptide. To find the right peptide among the infinite number of combinations, the
PreScreenArray project headed by Alexander Nesterov-Müller is aimed at further developing a parallel high-throughput screening method. Embedded in microscopic particles, the molecular peptide building blocks are transferred to discrete points on a surface, such that up to 25 million points will be located on one square centimeter. Combinatorial synthesis can be carried out in a highly dense format and the peptides to be synthesized can be tested for their properties more rapidly.
Press release on Prof. Nesterov-Müller’s ERC Grant (2011):
CellScreenChip – All-in-one Cell Screening Chip
Under the heading of personalized medicine, therapies are to be tailored to the individual patient to find e.g. the combination of drugs with the best effect and the least side effects for cancer patients. For this purpose, many cell cultures have to be treated with various substances in parallel. The CellScreenChip project headed by Pavel Levkin focuses on the miniaturization of the “dishes” for cell cultures by replacing them by single water droplets. The droplets are kept at a certain place and separated from each other by highly water-attracting or water-repellent surfaces.
Press release on Dr. Levkin‘s ERC Grant (2013):
Karlsruhe Institute of Technology (KIT) pools its three core tasks of research, higher education, and innovation in a mission. With about 9,300 employees and 25,000 students, KIT is one of the big institutions of research and higher education in natural sciences and engineering in Europe.
KIT – The Research University in the Helmholtz Association